The Los Angeles Rams and San Francisco 49ers open their 2026 NFL seasons with a historic NFC West showdown at the Melbourne Cricket Ground, the first regular-season NFL game ever played in Australia. Matthew Stafford and the Rams enter among the league’s leading contenders, while San Francisco arrive with Christian McCaffrey, Brock Purdy, George Kittle and a returning Nick Bosa looking to start the season by beating a familiar divisional rival on an unprecedented international stage.
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